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Time on Therapy Is the Variable That Moves Most The pivotal semaglutide obesity trial, STEP 1, ran 68 weeks in 1,961 adults and reported a mean change in body weight of 14.9% with semaglutide 2.4 mg versus 2.4% with placebo
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However, since semaglutide affects blood sugar and slows digestion, it can lead to side effects, particularly if mixed with alcohol
Reported in small human studies: Headache, dizziness, and transient blood pressure changes were noted in some early studies
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